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February 25, 2025

Chelsea Handler On How to Accept Your Mistakes and Make Drastic Changes!

Chelsea returns to celebrate her 50th birthday with MBB!!!

Chelsea Handler (comedian, television host, bestselling author) opens up about her transformative journey, from her powerful lessons on sisterhood learned from a tense meeting with Jane Fonda to the moment she realized her tough exterior was holding her back. Mayim breaks down her latest book, “I’ll Have What She’s Having” and Chelsea’s dating history, including her break-up with Jo Koy. Chelsea reveals how confronting deep-rooted anger fueled by childhood grief led her to therapy and spirituality, giving her the strength to evolve and embrace new forms of healing. Plus, she shares how turning 50 has reshaped her perspective on life, relationships, and finding freedom in saying "no"—a life-changing shift that’s led her to enjoy the freedom of not having kids while still embracing the joys of being a "stepmom" to many.

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Theme Song Written, Produced, and Performed by Ed Robertson. Mixed by Kenny Luong.
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Chelsea Handler

Comedian, Actress, Writer

chelseahandler
Mayim Bialik

Host

@missmayim
Jonathan Cohen

Co-Host

@jonathancohenofficial

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Guest References

I'll Have What She's Having
There’s a woman I want to become, Chelsea Handler thought as a child. She’ll be strong and confident. She’ll light up a room and spread that light to make others feel better. She’ll make a living being herself. She’ll be a survivor.
I'll Have What She's Having
There’s a woman I want to become, Chelsea Handler thought as a child. She’ll be strong and confident. She’ll light up a room and spread that light to make others feel better. She’ll make a living being herself. She’ll be a survivor.
See More