Judy Greer (Arrested Development, Marvel’s Ant-Man, 13 Going on 30, Halloween Kills) and Mayim relive the now legendary "Wil Wheaton fiasco", reminisce about THE BIG BANG THEORY (the role Judy continues to be recognized for most today) and their shared love for pickles and Taylor Swift! Judy reveals her powerful journey through perimenopause, from her symptoms and what encouraged her to seek help, to hormones and what has worked for her. She opens up about her body image & self-esteem issues, her thoughts on GLP-1 drugs (Ozempic, Mounjaro, Wegovy) and its effect on the body positivity movement. Judy discusses using alcohol as a reward and to ease social anxiety, sobriety and what it’s taught her about herself, her codependent tendencies, religion's role in processing grief, and how she finds ways to decompress after a particularly traumatic acting role. Mayim and Judy bond over their love of Taylor Swift! Judy recounts her Eras Tour experience and how Folklore made her a “Swiftie.” PLUS, she explains why her mom got fired from being a nun and why playing the "best friend" is her go-to role. Don't miss this raw and inspiring chat!

Andy Richter ( Conan, Madagascar, Three Questions with Andy Richter podcast) opens up about his childhood, mental health struggles, and his almost 30-year tenure as a late night tv sidekick. He details his experience with depression and lack of self-assuredness at an early age, and explains what lured him to performing. Andy describes the lack of agency and confusion he felt for being okay with his role as a sidekick, learning to be by himself and navigate the dating world after divorce, and what might be next for his professional career. Mayim and Andy consider the benefits of therapy and medication, the importance of mental healthcare for low income individuals, and the psychological benefits of having a dog. Mayim discusses ways to manage mental health while grieving in another installment of Ask Mayim Anything.

Dr. Gary Small, Professor of Psychiatry, Biobehavioral Sciences & Aging and Director of the UCLA Longevity Center, breaks down the biological causes and symptoms of aging and its impact on mental wellness. He discusses the effects of neurodegenerative memory disorders on patients and caregivers, his personal experiences with Alzheimer’s, and the toll his work with the difficult aspects of cognitive transitions takes on him. Mayim and Dr. Small examine the negative effects of stress and isolation on the aging process and how technology has the potential to help or harm it before delving into the ways we can strengthen our brains through meditation, sleep, therapy, social connections, learning a language or instrument, and even certain foods. They unpack the roles of the elderly in our society and the ways various cultures treat aging populations. Mayim opens up about her father’s degenerative condition, details common reasons we distract ourselves, and explains the Look-Snap-Connect techniques we can use to maintain and improve active brain health and memory.