Kevin Sussman (actor, writer, comedian, The Big Bang Theory) discusses his anxiety surrounding performing and reveals his process for tricking his brain into redirecting anxious thoughts. Mayim and Kevin reminisce about their shared experiences on the set of The Big Bang Theory and examine the differences between Kevin and his character, "Stuart Bloom." Kevin shares the advice George Clooney and Gary Shandling gave to him about combating anxiety and the body mechanics of the Alexander Technique he uses to manage habitual physical tension. Mayim breaks down the physiological symptoms and evolutionary advantages of anxiety, the science and cultural aspects of crying, and ways to avoid the trap of rumination. They discuss the benefits and side effects of anxiety medication and natural coping methods, and Mayim ends the episode with advice for managing anxiety when trying to fall asleep in the latest installment of Ask Mayim Anything.

Jackson Galaxy (Host & Executive Producer of My Cat from Hell, animal advocate, cat behavior expert, author, musician) opens up about his struggles with social anxiety, substance abuse, and disordered eating. After an illuminating installment of "What Mayim Hears", Jackson discusses growing up wanting to be a rock star and how playing guitar and busking at an early age helped him combat anxiety. He details his use of food as a comfort tool and alcohol as a social lubricant before he discovered the benefits provided by the structure of rituals. Mayim and Jackson break down how misdiagnoses and ineffective prescriptions can lengthen one’s mental health journey, the biological instincts tied to social anxiety, and navigating society as an empath. They bond over their shared love for the energetic minefield that is New York City, disordered eating as a public person, desires to be terminally unique involutes, and of course, their love of cats.

Salman “Sal” Khan, acclaimed educator and philanthropist describes his journey through the educational system and his plans to change it for the better. Originally an analyst at a hedge fund, Sal decided to leave his cushioned career in order to focus on his true passion, education. This is when https://www.khanacademy.org/ was born. Mayim and Sal discuss his vision of a world where everyone has the opportunity to receive individualized, compassionate education without the fear, stress, and anxiety of standardized tests and ranking systems. Mayim shares about her own experiences in the education system as a student and as a teacher to her children. Sal and Mayim discuss the “natural curiosity” of all human beings and comment on how the traditional education system has failed many students in many ways.